BANGLADESH PHARMACEUTICAL JOURNAL Vol. 15, No. 1 January 2012

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ISSN: 0301-4606 BANGLADESH PHARMACEUTICAL JOURNAL Vol. 15, No. 1 January 2012 EDITORIAL BOARD Editor-in-Chief Professor Dr. Md. Anwar Ul Islam Department of Pharmacy, Rajshahi University Executive Editor Dr. Md. Abdur Rashid Professor of Pharmaceutical Chemistry & Former Dean, s Professor A.Y.Sk. Firoz Uddin Ahmed Chowdhury Department of Pharmacy, Jahangirnagar University Professor Dr. Reza-ul Jalil Professor Dr. Md. Saiful Islam Professor Dr. Md. Sohel Rana Department of Pharmacy, Jahangirnagar University Dr. Md. Aslam Hossain Mr. Md. Hassan Kawsar Department of Pharmacy, Dhaka International University Mr. Md. Nasser Shahrear Zahedee Chairman, Radiant Pharmaceutical Ltd. Professor Dr. Nazmul Qais Professor Dr. Md. Selim Reza Mr. Md. Saiful Islam Pathan Department of Pharmacy, State University of Bangladesh Dr. Md. Khalid Hossain Dr. Mohiuddin Ahmed Bhuiyan Department of Pharmacy, University of Asia Pacific Advisors Professor Dr. Abdul Ghani Department of Pharmacy, Stamford University Bangladesh Professor Dr. Rebecca Banoo Professor Dr. Nurun Nahar Rahman Professor Dr. Choudhury Mahmood Hasan Published by: Bangladesh Pharmaceutical Society, 22 Dhanmondi R/A, Road 2, Dhaka-1205, Bangladesh E-mail: bps@agni.com, Web: www.bps-bd.org

Notice to Contributors Bangladesh Pharmaceutical Journal is an international and multidisciplinary research and review journal, published by Bangladesh Pharmaceutical Society in January and July of each year. Original research papers or review articles are accepted on the understanding that they are subject to editorial revision, that their contents have not been published elsewhere and that in consideration of acceptance of a text for publication the copyright of the said text is assigned to the Bangladesh Pharmaceutical Journal. Contributions Manuscripts for publication and communications or concerning editorial matters should be sent to the Editor-in-Chief through E- mail: bpjeditor@ yahoo.com. A copy of the same should also be sent to the Executive Editor through e-mail: bpjexecutiveeditor @yahoo.com Preparation of Text Authors should consult a CURRENT issue of the journal and conform to the typographical conventions, use of headings, layout of tables and citation of references. Texts must be computer composed (MS office programs should be used in preparing the texts, charts and graphs) in double spacing and printed in one side of A4 size offset paper, with a minimum margin of 1 inch on all sides. Two sets of hard copies should be submitted along with soft copy in CD. The articles may also be sent through E-mail to the Editor-in-Chief or to the Executive Editor. The name(s) of the contributor(s), affiliation of the laboratory where the work was done and a shortened title should accompany the typescript. A summary page should be included, describing results and conclusions in the form of ABSTRACT suitable for use as such by the abstracting journals. It should not exceed 250 words. A list of 3-6 Keywords should be supplied by the authors. References All citations in the text must appear in the References list and vice versa. In the text, the reference should appear as either: Ghani (1984) described, or As described previously (Ghani, 1984). When there are more than two authors, mention only the first author, e.g. Ghani et al., 1984. If the year is same for several references identify these with a,b,c, etc. e.g. Ghani (1975a,b,c) both in the text and in the Reference list. In the Reference list, arrange the references in alphabetical order. References should follow the format shown: Khan, S., Jabbar, A., Hasan, C.M. and Rashid, M.A. 2000. Nasimaluns A and B: neo-clerodane diterpenoids from Barringtonia racemosa. J. Nat. Prod. 63, 410-411. Rashid, M.A., Gustafson, K.R., Crouch, R.C., Groweiss, A., Pannell, L.K., Van, Q.N. and Boyd, M.R. 2002. Application of high-field NMR and cryogenic probe technologies in the structure elucidation of poecillastrin A, a new antitumor macrolide lactam from the sponge Poecillastra species. Org. Lett. 4, 3293-3296. Mabry, T., Markham, K.R. and Thomas, M.B. 1971. The Systematic Identification of Flavonoids. Springer Verlag, New York, p. 43. Harborne, J.B. 1983. In: Chemistry and Chemical Taxonomy of the Rutales (Waterman, P.G. and Grundon, M.F., Eds.), Academic Press, London, Chapter 2, pp. 147-173. Hasan, C.M. 1982. Phytochemical studies on some African Annonaceae. Ph. D. Thesis, University of Strathclyde, U.K., p. 35. Abbreviations Abbreviations are used without periods. Standard abbreviations should be used throughout the manuscript. The preferred forms of some of the more commonly used abbreviations are mp, bp, C, K, s, min, h, ml, µl, kg, g, mg, µg, cm, mm, nm, mol, mmol, µmol, ppm, TLC, GC, NMR, MS, UV, IR, etc. Tables Tables should be typed in appropriate places in the text and numbered consecutively using Arabic numerals (e.g. 1, 2, 3). Their headings should briefly describe their contents. Graphs and Photographs All graphs and charts should be made with either MS Excel or Harvard Graphics software along with title and legends. Photographs, either coloured or black & white should be developed on glossy paper. Title and legends of the photographs should be typed at the end of the manuscript. The photographs should also be marked at the back with figures number and title of the paper. If the author scans a photograph, the preferable file formats are Adobe photoshops, JPEG, PSD, BMP. The resolution should not be less than 200 and the size of the photographs should be at least double. Proofs and Reprints Galley proofs will be sent to the corresponding author, which s/he is requested to correct and return as soon as possible. No new matter be inserted in the text and no changes be made in the title or author name(s) at the time of proof reading. Corresponding author will receive 10 reprints free of charge. Declaration All authors are requested to sign a declaration that the work described in the manuscript was carried out by them and the contents of the paper have not been published before or submitted elsewhere for publication. When the number of authors/co-authors is more than one, the corresponding author is required to mention the exact contribution of each co-author and also indicate his/her percentage of contribution. Editorial Office Bangladesh Pharmaceutical Journal C/o. Bangladesh Pharmaceutical Society 22 Dhanmondi R/A, Road 2, Dhaka-1205, Bangladesh E-mail: bps@agni.com, Web: www.bps-bd.org Bangladesh Pharmaceutical Society. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without the prior permission of the Bangladesh Pharmaceutical Society.

BANGLADESH PHARMACEUTICAL JOURNAL Vol. 15, No. 1 January 2012 CONTENTS Evaluation of Bioactivities of Nymphaea nouchali (Burm. f) - the National Flower of Bangladesh Md. Al Amin Sikder, Hasnin Rahman Jisha, Md. Ruhul Kuddus, Farhana Rumi, Mohammad A. Kaisar and Mohammad A. Rashid Study of Differential Scanning Calorimetry of complex of Magnesium Sulfate with Aspirin, Paracetamol and Naproxen Sangita Paul Kundu, Farhad Mohammad Amjad, Sania Sultana, Md. Zakir Sultan, Mohammad Amjad Hossain and Mohammad Shah Amran In vitro Antibacterial and Cytotoxic activities of Compounds Isolated from Streptomyces sp. MBS-15 Mohitosh Biswas, Md. Ajijur Rahman, Hajera khatun and Md. Anwar-Ul Islam Formulation and Evaluation of Sustained Release Matrix Type Transdermal Film of Ibuprofen Shahida Jannat, Md. Abdullah Al Masum, Florida Sharmin, S M Ashraful Islam and Md. Selim Reza Interaction of 1-Pyrrolidine Carbodithioic Acid with Cu(II), Ni(II) and Co(II) ions Ferdousi Khan, Md. Abdus Salam, Md. Arifur Rahman, Abdus Salam, A.M. Shafiqul Alam and Md. Amjad Hossain Preliminary Screening of Six Popular Fruits of Bangladesh for in vitro IgM Production and Proliferation of Splenocytes Md. Moklesur Rahman Sarker, Ishrat Nimmi and Md. Hassan Kawsar Binding of Valsartan to Bovine Serum Albumin: an in vitro Study S. M. Shareful Islam, M. K. Hossain, S. Kabir, Muhammad Rakib Al-Mamun, A. N. M Hamidul Kabir and M. A. Mazid Preliminary Antimicrobial and Antihyperglycemic Activities of Mariscus sumatrensis Jamiuddin Ahmed, Md. Nur Alam, Nazia Hoque, Md. Sohel Rana, Moynul Hasan and Md. Hossain Sohrab Development and Validation of a Simple and Rapid UV Spectrophotometric Method for Assay of Nitazoxanide in Pharmaceutical Dosage Forms Fahima Aktar, Md. Ruhul Kuddus, Akter Hossen, Md. Khalid Hossain and Mohammad A. Rashid Effect of Barium Chloride as a Cross Linking Agent on the Sodium Alginate Based Diclofenac Sodium Beads Md. Masud Morshed, Jewel Mallick, Aninda Kumar Nath, Md. Zia Uddin, Mycal Dutta, Md. Akbar Hossain and Md. Hassan Kawsar Ethnomedical Studies of Chakma Communities of Chittagong Hill Tracts, Bangladesh Tuhin Khisha, Reatul Karim, Sharmin Reza Chowdhury and Rebecca Banoo 1 7 13 17 23 31 39 43 47 53 59 Antioxidant and Cytotoxic Activities of Mussaenda macrophylla Farhana Islam, Tasdique Mohammad Quadery, Sharmin Reza Chowdhury, Mohammad Abul Kaisar, Md. Gias Uddin and Mohammad A. Rashid 69

Studies to Improve Dissolution Properties of Poorly Soluble Carbamazipine by Solid Dispersion Md. Aminul Haque, Md. Faizul Hasan, Irin Dewan, S.M. Ashraful Islam and Mohiuddin Ahmed Bhuiyan Impact of Sodium Lauryl Sulphate on the Release of Carbamazepine from Methocel K15M CR based Matrix Tablets Md. Shaikhul Millat Ibn Razzak, Ferdous Khan, Masuma Hossain, Tasmia Anika and Shamsad Afreen Moon Synthesis and Antimicrobial Studies of Copper (II) Metal Complexes that Specifically Recognize Nucleic Acid Bases A.K. M. Nur Alam Siddiki, Md. Shahidur Rahman, Mohammad Arifur Rahman, Md. Abdus Salam, Abdus Salam, Md. Abu Yousuf, Md. Farhadul Islam and Md. Azharul Arafat Effect of Superdisintegrants on Some Physical Attributes and Release Profile of Paracetamol Immediate Release Tablets Abu Afzal Mohammad Shakar, Md. Shaikhul Millat Ibn Razzak, Md. Mofazzal Hossain, Md. Hasanul Arif and Md. Selim Reza 73 79 83 89 Uraria lagopodies DC. shows Antimicrobial, Antioxidant, Antidiarrhoeal, Antidepressant and Cytotoxic Activities Md. Torequl Islam, Mohammed Ibrahim, A.K.M. Moyeenul Huq, M. Mohi Uddin Chowdhury, Md. Aslam Hossain and Mohammad A. Rashid Recent Pharma News 99 New Drugs Approved 101 95

Bangladesh Pharmaceutical Society (BPS) Central Executive Council Name & Portfolio Mr. Md. Nasser Shahrear Zahedee President Professor Dr. Md. Anwar Ul Islam Vice President Mr. M. Azizul Huq Vice President Mr. Md. Hassan Kawsar General Secretary Mr. Akhil Dutta Joint Secretary Mr. Muhammad Mahbubul Haq Joint Secretary Mr. Md. Mahbubul Islam Finance Secretary Mr. Mohammad Shamsul Alam Organizing Secretary Dr. Md. Aslam Hossain Publication Secretary Professor A.Y. Sk. Feroz Uddin Ahmed Chowdhury Mr. Md. Amzad Hussain Mr. Md. Rahmat Ullah Mr. Ahsanul Habib Rumi Mr. Md. Abul Khair Chowdhury Mr. Md. Saiful Islam Pathan Mr. Md. Habibul Kibria Dr. Md. Khalid Hossain Mr. Mohammad Ashraful Alam Mr. Md. Mazharul Ahsan Institutional Affiliation Chairman, Radiant Pharmaceuticals Limited 22 Dhanmondi, Road-2, Dhaka- 1205 Department of Pharmacy Rajshahi University, Rajshahi Managing Director, GlaxoSmithKline Gulshan-1, Dhaka Chairman, Department of Pharmacy Dhaka International University, Banani, Dhaka General Manager Techno Drugs, Narshingdi Assistant Secretary Pharmacy Council of Bangladesh, Dhaka General Manager, Drug International Ltd. Tongi Industrial Area, Gazipur-1710 Senior Officer (IB), Radiant Pharmaceutical Limited 22 Dhanmondi, Road No. 2, Dhaka-1205 Associate Professor, Faculty of Pharmacy University of Dhaka, Dhaka-1000 Department of Pharmacy Jahangirnagar University, Savar, Dhaka Factory Manager, Alco Pharmaceutical Ltd. Mirpur, Dhaka Managing Director, Ethical Drugs Ltd. 9 Hatkhola, Dhaka Chief Operating Officer, Novo Healthcare and Pharma Ltd. Mirpur, Dhaka Deputy Director Directorate General of Drug Administration, Dhaka Associate Professor, Department of Pharmacy State University of Bangladesh, Dhaka Lecturer Sir Salimullah Medical College & Hospital, Dhaka Associate Professor, Faculty of Pharmacy University of Dhaka, Dhaka-1000 Product Promotion Manager, Radiant Pharmaceutical Limited 22 Dhanmondi, Road-2, Dhaka- 1205 General Manager, Organic Health Care 64/5, RK Mission Road, Sutrapur, Dhaka. Computer formatted by: Hasib Computers & Printing, 62/1, Purana Paltan, Dhaka-1000, Bangladesh Phone: 01552-388130, 9016429 (Res.), E-mail: hcomputer05@yahoo.com Printed by: Asiatic Civil Military Press, 43/10 C, Swamibag, Dhaka-1100, Bangladesh. Phone: 7120428